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1,1-Dimethylbiguanide-[13C4,15N5] hydrochloride

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1,1-Dimethylbiguanide-[13C4,15N5] hydrochloride

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General Information
Catalog: BLP-005552
Molecular Formula: [13C]4[15N]5H12Cl
Molecular Weight: 174.56

Chemical Structure

Description	1,1-Dimethylbiguanide-[13C4,15N5] hydrochloride, a labelled isotope analogue of 1,1-Dimethylbiguanide hydrochloride (Metformin hydrochloride), which inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy. Metformin decreases hyperglycemia primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). 1,1-Dimethylbiguanide-13C4,15N5 hydrochloride can be also used as a standard for the analysis of Metformin hydrochloride and is useful in the research of mechanism of Metformin hydrochloride Metabolic route.
IUPAC Name	3-[bis(15N)(azanyl)(1-13C)methylidene]-1,1-di((1-13C)methyl)(13C)guanidine;hydrochloride
Related CAS	1115-70-4 (unlabelled)
Canonical SMILES	CN(C)C(=N)N=C(N)N.Cl
InChI	InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H/i1+1,2+1,3+1,4+1,5+1,6+1,7+1,8+1,9+1;
InChI Key	OETHQSJEHLVLGH-GNXMHKIVSA-N
Purity	97% by CP; ≥99% atom 13C
Appearance	White Powder

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