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Application Area
Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic
Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry
Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

1,1-Dimethylbiguanide-[13C4,15N5] hydrochloride

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General Information
Catalog: BLP-005552
Molecular Formula: [13C]4[15N]5H12Cl
Molecular Weight: 174.56
Chemical Structure
1,1-Dimethylbiguanide-[13C4,15N5] hydrochloride
Description 1,1-Dimethylbiguanide-[13C4,15N5] hydrochloride, a labelled isotope analogue of 1,1-Dimethylbiguanide hydrochloride (Metformin hydrochloride), which inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy. Metformin decreases hyperglycemia primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). 1,1-Dimethylbiguanide-13C4,15N5 hydrochloride can be also used as a standard for the analysis of Metformin hydrochloride and is useful in the research of mechanism of Metformin hydrochloride Metabolic route.
IUPAC Name 3-[bis(15N)(azanyl)(1-13C)methylidene]-1,1-di((1-13C)methyl)(13C)guanidine;hydrochloride
Related CAS 1115-70-4 (unlabelled)
Canonical SMILES CN(C)C(=N)N=C(N)N.Cl
InChI InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H/i1+1,2+1,3+1,4+1,5+1,6+1,7+1,8+1,9+1;
InChI Key OETHQSJEHLVLGH-GNXMHKIVSA-N
Purity 97% by CP; ≥99% atom 13C
Appearance White Powder
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