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1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropane-2,2,3,3-[d4]-carbonitrile

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General Information
Catalog: BLP-020985
CAS: 1961281-88-8
Molecular Formula: C11H3D4F2NO2
Molecular Weight: 227.2

Chemical Structure

Description	1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropane-2,2,3,3-d4-carbonitrile is an intermediate in the synthesis of Tezacaftor-D4 (T321512), an isotope labelled compound of Tezacaftor (T321510). Tezacaftor is used as a combination therapy with Ivacaftor for the treatment of patients with cystic fibrosis.
Appearance	Off-white solid