Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-011425 |
CAS: 327178-90-5 |
Molecular Formula: C22H19D27NO7P |
Molecular Weight: 494.74 |
Chemical Structure |
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Description | 14:0-[d27] Lyso PC is a labelled compound of 1-Myristoyl-sn-glycero-3-phosphocholine. 1-Myristoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine derivative, which is found in plasma and oxidized low-density lipoprotein (Ox-LDL). It can be used as a biomarker for detecting lipid metabolism. |
Synonyms | 1-myristoyl-d27-sn-glycero-3-phosphocholine |
Related CAS | 20559-16-4 (unlabelled) |
Purity | >99% |
Appearance | Powder |
Shelf Life | 1 Year |
Storage | Store at −20°C |
14:0-[d27] Lyso PC is a deuterated lipid molecule used in various bioscience applications. Here are some key applications of 14:0-[d27] Lyso PC:
Lipidomics Research: In lipidomics, 14:0-[d27] Lyso PC serves as an internal standard for mass spectrometry analysis of lipid profiles. Its deuterated nature allows for precise quantification and differentiation from native lipid species. This helps researchers identify and analyze lipid alterations in different biological samples, essential for studying metabolic diseases or physiological states.
Membrane Dynamics Studies: 14:0-[d27] Lyso PC is used to investigate the biophysical properties of biological membranes. By incorporating this molecule into lipid bilayers, scientists can study membrane fluidity, phase transitions, and interactions with proteins or other lipids. These insights are crucial for understanding membrane functionality and the role of lipids in cellular signaling and structure.
Drug Delivery Systems: This deuterated lipid is also utilized in the development of liposomal drug delivery systems. The incorporation of 14:0-[d27] Lyso PC into liposomes can enhance their stability and targeting ability. Studies using these systems can inform the design of more effective lipid-based carriers for therapeutics, improving drug bioavailability and minimizing side effects.
Nutritional Studies: In nutritional research, 14:0-[d27] Lyso PC is deployed as a tracer to study phospholipid metabolism. By tracking the assimilation and turnover of this labeled lipid in biological systems, researchers can gain insights into dietary lipid absorption and utilization. This information is valuable in understanding lipid-related health conditions and optimizing nutritional strategies.
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