Name: 16:0 Lyso PC-[d49]
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-011324

CAS: 2315262-40-7

Molecular Formula: C24HD49NO7P

Molecular Weight: 544.93

Chemical Structure

Synonyms	1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine (d49); 16:0 Lyso PC-d49; 1-Palmitoyl-sn-glycero-3-phosphocholine-d49; 1-hexadecanoyl-sn-glycero-3-phosphocholine-d49; Lyso PC(16:0)-d49; 1-palmitoyl-phosphatidylcholine-d49; LPC(16:0/0:0)-d49; LysoPC(16:0/0:0)-d49; Lysophosphatidylcholine(16:0/0:0)-d49; Ethan-1,1,2,2-d4-aminium, 2-[[hydroxy[[(2R)-2-hydroxy-3-[(1-oxohexadecyl-2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,16-d31)oxy]propyl-1,1,2,3,3-d5]oxy]phosphinyl]oxy]-N,N,N-tri(methyl-d3)-, inner salt
IUPAC Name	3-((hexadecanoyl-d31)oxy)-2-hydroxypropyl-1,1,2,3,3-d5 (2-(tris(methyl-d3)ammonio)ethyl-1,1,2,2-d4) phosphate
Related CAS	17364-16-8 (unlabelled)
Canonical SMILES	[2H][C@@](O)(C([2H])([2H])OC(=O)C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])C([2H])([2H])OP([O-])(=O)OC([2H])([2H])C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
InChI	InChI=1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1/i1D3,2D3,3D3,4D3,5D2,6D2,7D2,8D2,9D2,10D2,11D2,12D2,13D2,14D2,15D2,16D2,17D2,18D2,19D2,20D2,21D2,22D2,23D
InChI Key	ASWBNKHCZGQVJV-MPIXDXTJSA-N
Purity	>99%
Appearance	White Solid
Shelf Life	1 Year
Storage	Store at -20°C

16:0 Lyso PC-[d49], a deuterated lipid widely utilized in lipidomics and diverse bioscience applications, plays a pivotal role in various fields. Here are key applications showcased with high perplexity and burstiness:

Mass Spectrometry Calibration: Serving as an internal standard in mass spectrometry for lipid profiling, 16:0 Lyso PC-[d49] emerges as a beacon of accuracy amidst the intricate landscape of lipid analysis. Its stable isotope labeling facilitates precise quantification of phospholipids in complex biological samples, ensuring the integrity of lipidomics studies through meticulous calibration and validation processes.

Membrane Dynamics Studies: Delving into the realm of membrane dynamics, researchers harness the power of 16:0 Lyso PC-[d49] to navigate the complex web of lysophosphatidylcholines within cellular membranes. By introducing this labeled entity into cell membranes, scientists embark on a journey of exploration, tracing subtle changes in lipid composition and unraveling the intricate ballet of molecular interactions using state-of-the-art imaging techniques. This newfound knowledge illuminates cellular phenomena such as signaling cascades and membrane fusion events, painting a vibrant picture of cellular life's intricate choreography.

Pharmacokinetics Research: Acting as a cornerstone in pharmacokinetics, 16:0 Lyso PC-[d49] shines as a beacon of hope for deciphering the mysteries of lipid-related drug behavior within biological systems. With its distinct deuterated nature, this compound offers a clear guidepost in the turbulent sea of drug metabolism studies, enabling researchers to investigate the absorption, distribution, metabolism, and excretion pathways of lipid-based pharmaceuticals with unparalleled clarity. Through this lens, researchers can refine drug formulations and unravel the enigmatic behaviors of lipid drug carriers, paving the way for more effective therapeutic interventions.

Metabolic Studies: In the intricate tapestry of metabolic research, 16:0 Lyso PC-[d49] emerges as a trailblazer, shedding light on the dark corners of lipid metabolism pathways with its penetrating gaze. As a trusted tracer, it embarks on a journey through the labyrinthine pathways of lipid biosynthesis and degradation, unveiling the enigmatic processes governing metabolic equilibrium. Through meticulous observation of its incorporation and turnover within metabolic cascades, researchers glean valuable insights into metabolic disorders and forge new pathways toward therapeutic interventions, unlocking the potential for transformative breakthroughs in the realm of metabolic medicine.