| Description |
[(1S,2R)-3-[[(4-Nitrophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-phenylmethyl)propyl]carbamic Acid (3S)-Tetrahydro-3-furanyl Ester-[d4] is the labelled analogue of [(1S,2R)-3-[[(4-Nitrophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-phenylmethyl)propyl]carbamic Acid (3S)-Tetrahydro-3-furanyl Ester, which is an intermediate in the synthesis of Amprenavir, a selective HIV protease inhibitor. |
| Synonyms |
[(1S,2R)-3-[[(4-Nitrophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-phenylmethyl)propyl]carbamic-D4, (3S)-Tetrahydro-3-furanyl Ester; [(3S)-oxolan-3-yl] N-[(2S,3R)-3-hydroxy-4-[2-methylpropyl-(4-nitrophenyl)sulfonylamino]-1-phenylbutan-2-yl]carbamate-d4 |
| IUPAC Name |
[(3S)-oxolan-3-yl] N-[(2S,3R)-3-hydroxy-4-[2-methylpropyl-(2,3,5,6-tetradeuterio-4-nitrophenyl)sulfonylamino]-1-phenylbutan-2-yl]carbamate |
| Related CAS |
160231-69-6 (unlabelled)
|
| Canonical SMILES |
CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)O)S(=O)(=O)C3=CC=C(C=C3)[N+](=O)[O-] |
| InChI |
InChI=1S/C25H33N3O8S/c1-18(2)15-27(37(33,34)22-10-8-20(9-11-22)28(31)32)16-24(29)23(14-19-6-4-3-5-7-19)26-25(30)36-21-12-13-35-17-21/h3-11,18,21,23-24,29H,12-17H2,1-2H3,(H,26,30)/t21-,23-,24+/m0/s1/i8D,9D,10D,11D |
| InChI Key |
ZMNCIAGFQBUWTJ-MHVPRHJPSA-N |
| Purity |
>98% |
| Solubility |
Slightly soluble in Chloroform, Methanol |
| Appearance |
Off-white Solid |
| Storage |
Store at -20°C |
amino]-2-hydroxy-1-phenylmethyl)propyl]carbamic Acid, (3S)-Tetrahydro-3-furanyl Ester-[d4]](/isotope.v1/images/structure-default.jpg)
