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2-[2-(Methyl-[d3]-thio)ethyl-1,1,2,2-[d4]]-1H-isoindole-1,3(2H)-dione

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2-[2-(Methyl-[d3]-thio)ethyl-1,1,2,2-[d4]]-1H-isoindole-1,3(2H)-dione

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General Information
Catalog: BLP-016979
CAS: 1009307-40-7
Molecular Formula: C11H4D7NO2S
Molecular Weight: 228.32

Chemical Structure

Description

2-[2-(Methyl-d3-thio)ethyl-1,1,2,2-d4]-1H-isoindole-1,3(2H)-dione is an intermediate used in the synthesis of Lapatinib-d7 Dihydrochloride (L175807), which is a labeled Lapatinib (L175800), a reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic;Also, it is used in the preparation of 4-Aminoquinazolines as EGFR and HER-2 inhibitors.