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2,5-Dimethoxytetrahydrofuran-2,3,3,4,4,5-[d6]

General Information
Catalog: BLP-005640
Molecular Formula: C6H6D6O3
Molecular Weight: 138.19
Chemical Structure
2,5-Dimethoxytetrahydrofuran-2,3,3,4,4,5-[d6]
Description 2,5-Dimethoxytetrahydrofuran-2,3,3,4,4,5-[d6] is intended for use as an internal standard for 2,5-Dimethoxytetrahydrofuran. 2,5-Dimethoxytetrahydrofuran-2,3,3,4,4,5-[d6], as a heterocyclic building block, can be also used as a reagent in the synthesis of D labelled tropinone.
IUPAC Name 2,3,3,4,4,5-hexadeuterio-2,5-dimethoxyoxolane
Related CAS 696-59-3 (unlabelled)
Canonical SMILES COC1CCC(O1)OC
InChI InChI=1S/C6H12O3/c1-7-5-3-4-6(8-2)9-5/h5-6H,3-4H2,1-2H3/i3D2,4D2,5D,6D
InChI Key GFISDBXSWQMOND-VYXNDPKGSA-N
Boiling Point 145-147°C
Purity 98% by CP; 98% atom D
Density 1.02 g/mL at 25°C
Appearance Clear Colorless Liquid

2,5-Dimethoxytetrahydrofuran-2,3,3,4,4,5-[d6] is a deuterated compound primarily used in scientific research due to its unique properties. Here are some key applications of 2,5-Dimethoxytetrahydrofuran-2,3,3,4,4,5-[d6]:

NMR Spectroscopy: In nuclear magnetic resonance (NMR) spectroscopy, 2,5-Dimethoxytetrahydrofuran-2,3,3,4,4,5-[d6] is utilized as a solvent or standard due to its deuterated nature. Its deuterium atoms replace hydrogen, reducing background interference and allowing for clearer spectral analysis. This aids researchers in obtaining more accurate and detailed insights into the structural and dynamic properties of molecules.

Chemical Synthesis: In organic chemistry, this compound can serve as a reagent in various synthetic pathways. Deuterium labeling with 2,5-Dimethoxytetrahydrofuran-2,3,3,4,4,5-[d6] allows chemists to trace molecular transformations and reaction mechanisms. As a result, it plays a significant role in advancing the understanding of chemical reactions and the development of novel compounds.

Pharmacokinetic Studies: The compound is useful in pharmacokinetic studies to investigate drug absorption, distribution, metabolism, and excretion. By incorporating deuterium, researchers can track the fate of drug molecules within biological systems without altering their properties. This application provides critical data needed for drug development and safety assessments.

Isotope Effects Research: In studies exploring isotope effects, 2,5-Dimethoxytetrahydrofuran-2,3,3,4,4,5-[d6] serves as a valuable research tool. The presence of deuterium can influence reaction rates and mechanisms, providing insights into kinetic and thermodynamic properties. This knowledge is essential for understanding processes such as enzyme catalysis and isotope fractionation.

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