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2-deoxy-D-ribose-[tri-O-d]

General Information
Catalog: BLP-006985
Molecular Formula: C5H7D3O4
Molecular Weight: 137.15
Chemical Structure
2-deoxy-D-ribose-[tri-O-d]
Synonyms 2-deoxy-D-[tri-O-2H]ribose; 2-deoxy-D-[tri-O-2H]erythro-pentose; 2-deoxy-D-ribose-tri-O-d
IUPAC Name (3S,4R)-tetrahydro-2H-pyran-2,3,4-triol-d3
Related CAS 533-67-5 (unlabelled)
Storage Store at -20°C

2-deoxy-D-ribose-[tri-O-d], a labeled sugar molecule widely employed in various scientific studies, offers a multitude of applications:

Metabolic Tracking: Employing 2-deoxy-D-ribose-[tri-O-d] for tracking metabolic processes in cells provides invaluable insights. By introducing this labeled sugar into cells, researchers can monitor metabolic flux and pathway utilization across varied conditions. This method facilitates precise analysis of energy storage and consumption dynamics within biological systems, shedding light on intricate metabolic networks.

Nucleic Acid Research: In the realm of nucleic acid metabolism, the utilization of this compound as a marker is paramount. Facilitating the study of DNA and RNA synthesis, 2-deoxy-D-ribose-[tri-O-d] serves as a crucial component in nucleotide incorporation studies. Its labeled form enables accurate measurement and analysis of nucleic acid turnover rates and mechanisms, contributing to a comprehensive understanding of genetic processes.

Radiolabeling in Diagnostic Imaging: Harnessing 2-deoxy-D-ribose-[tri-O-d] as a radiolabeled sugar in diagnostic imaging techniques yields significant advancements. Particularly in PET scans, this compound enables precise mapping of glucose uptake and utilization in tissues, aiding in the detection of cancerous cells and metabolic disorders. Such applications hold profound implications for early disease diagnosis and monitoring disease progression with heightened accuracy.

Glycosylation Studies: Delving into the intricacies of glycosylation processes, researchers leverage this compound to study protein and lipid modifications. With glycosylation being a pivotal post-translational modification influencing protein function, 2-deoxy-D-ribose-[tri-O-d] provides a means to elucidate the roles and mechanisms of glycosylation in cellular functions and disease states. This avenue of study offers crucial insights into fundamental biological processes with implications for disease pathogenesis.

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