| Description |
2-Hydroxy Atorvastatin Acetonide tert-Butyl Ester-[d5] is the labelled analogue of 2-Hydroxy Atorvastatin Acetonide tert-Butyl Ester, which is a metabolite of Atorvastatin. |
| Synonyms |
2-Hydroxy Atorvastatin-D5 Acetonide tert-Butyl Ester |
| IUPAC Name |
tert-butyl 2-[(4R,6R)-6-[2-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-3-(2,3,4,5,6-pentadeuteriophenyl)-5-propan-2-ylpyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate |
| Related CAS |
265989-40-0 (unlabelled)
|
| Canonical SMILES |
CC(C)C1=C(C(=C(N1CCC2CC(OC(O2)(C)C)CC(=O)OC(C)(C)C)C3=CC=C(C=C3)F)C4=CC=CC=C4)C(=O)NC5=CC=CC=C5O |
| InChI |
InChI=1S/C40H47FN2O6/c1-25(2)36-35(38(46)42-31-15-11-12-16-32(31)44)34(26-13-9-8-10-14-26)37(27-17-19-28(41)20-18-27)43(36)22-21-29-23-30(48-40(6,7)47-29)24-33(45)49-39(3,4)5/h8-20,25,29-30,44H,21-24H2,1-7H3,(H,42,46)/t29-,30-/m1/s1/i8D,9D,10D,13D,14D |
| InChI Key |
OZJAGODXZFIYDA-REWGUOJHSA-N |
| Boiling Point |
694.8±55.0 °C at 760 mmHg |
| Purity |
95% atom D |
| Density |
1.2±0.1 g/cm3 |
| Solubility |
Soluble in Acetone, Chloroform, Dichloromethane, Ethyl Acetate |
| Appearance |
White Foamy Solid |
| Application |
A deuterated intermediate of the metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with |
| Storage |
Store at -20°C |
![2-Hydroxy Atorvastatin Acetonide tert-Butyl Ester-[d5]](https://resource.bocsci.com/structure/265989-42-2.gif)
