Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-000894 |
Molecular Formula: C16[13C]5H20Cl2FN4[15N]O2.HCl |
Molecular Weight: 506.74 |
Chemical Structure |
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Description | 2-Keto Crizotinib-[13C5,15N] is the labelled analogue of 2-Keto Crizotinib. 2-Keto Crizotinib is an impurity of Crizotinib, a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent. |
Synonyms | [13C5,15N]-Crizotinib metabolite hydrochloride |
IUPAC Name | 4-(4-(6-amino-5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-2-one-2,3,4,5,6-13C5-1-15N |
Related CAS | 1415558-82-5 (unlabelled free base) |
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