| Description |
2-Methylthio-N6-isopentenyladenosine-[d6] is the labelled analogue of 2-Methylthio-N6-isopentenyladenosine, which is located at position 37 in tRNAs that reads codons starting with uridine. It improves the efficiency of tRNA in trpT (Su9) inhibitory tRNA by protecting the tRNA from ribosome proofing induced by the codon environment. |
| Synonyms |
2-Methylthio-N6-isopentenyladenosine-d6; N-[3-(Methyl-d3)-2-buten-1-yl-4,4,4-d3]-2-(methylthio)-Adenosine; N-(3-Methyl-2-butenyl)-2-(methylthio)-adenosine-d6; 2-Methylthio-6-(3-methyl-2-butenylamino)-β,D-ribofuranosylpurine-d6; 2-Methylthio-N6-(isopenten-2-yl)adenosine-d6; 2-Methylthio-N6-(Δ2-isopentenyl)adenosine-d6; 2-Methylthio-N6-(γ,γ-dimethylallyl)adenosine-d6; 2MSA-d6; 6-(3-Methyl-2-butenylamino)-2-methylthio-9-β-D-ribofuranosylpurine-d6; 6-(3-Methyl-2-butenylamino)-2-methylthiopurine Riboside-d6; N6-(3-Methyl-2-butenyl)-2-(methylthio)adenosine-d6; N6-(Δ2-Isopentenyl)-2-methylthioadenosine-d6; ms2i6A-d6 |
| IUPAC Name |
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((3-(methyl-d3)but-2-en-1-yl-4,4,4-d3)amino)-2-(methylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol |
| Related CAS |
20859-00-1 (unlabelled)
|
| Canonical SMILES |
CC(=CCNC1=C2C(=NC(=N1)SC)N(C=N2)C3C(C(C(O3)CO)O)O)C |
| InChI |
InChI=1S/C16H23N5O4S/c1-8(2)4-5-17-13-10-14(20-16(19-13)26-3)21(7-18-10)15-12(24)11(23)9(6-22)25-15/h4,7,9,11-12,15,22-24H,5-6H2,1-3H3,(H,17,19,20)/t9-,11?,12?,15-/m1/s1/i1D3,2D3 |
| InChI Key |
VZQXUWKZDSEQRR-FUYJEUCRSA-N |
![2-Methylthio-N6-isopentenyladenosine-[d6]](https://resource.bocsci.com/structure/1258839-12-1.gif)
