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Application Area
Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic
Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry
Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

3,4-Diaminopyridine-[d3]

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General Information
Catalog: BLP-002662
Molecular Formula: C5H4D3N3
Molecular Weight: 112.15
Chemical Structure
3,4-Diaminopyridine-[d3]
Description 3,4-Diaminopyridine-[d3] is the labelled analogue of Amifampridine. Amifampridine is a drug, predominantly in the treatment of a number of rare muscle diseases. It is used to treat many of the congenital myasthenic syndromes, particularly those with defects in choline acetyltransferase, downstream kinase 7, and those where any kind of defect causes ''fast channel'' behaviour of the acetylcholine receptor.
Synonyms 3,4-Diaminopyridine D3; 3,4-DAP-d3; 4,5-Diaminopyridine-d3; Amifampridine-d3; DAP-d3; NSC 521760-d3; Pyridine-4,5-diamine-d3; 3,4-Diamino-pyridine-d3; 3,4-Pyridinediamine-d3
IUPAC Name 2,5,6-Trideuteriopyridine-3,4-diamine
Related CAS 54-96-6 (unlabelled)
Canonical SMILES C1=CN=CC(=C1N)N
InChI InChI=1S/C5H7N3/c6-4-1-2-8-3-5(4)7/h1-3H,7H2,(H2,6,8)/i1D,2D,3D
InChI Key OYTKINVCDFNREN-CBYSEHNBSA-N
Melting Point > 218 °C (dec.)
Purity 97%; > 95% atom D
Solubility Slightly soluble in DMSO, Methanol
Appearance White to Off-white Solid
Storage -20 °C under inert atmosphere
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