CAS 1329837-80-0 4-(4-Aminophenyl)-3-morpholinone-[d4]

General Information
Catalog: BLP-012977
CAS: 1329837-80-0
Molecular Formula: C10H8D4N2O2
Molecular Weight: 196.24

General Information

Catalog: BLP-012977

CAS: 1329837-80-0

Molecular Formula: C10H8D4N2O2

Molecular Weight: 196.24

Chemical Structure

Description	4-(4-Aminophenyl)-3-morpholinone-[d4] is the labelled analogue of 4-(4-Aminophenyl)-3-morpholinone, which could be used as a reagent in the synthesis of Morpholine based pharmaceuticals.
Synonyms	4-(4-Aminophenyl)-3-morpholinone-d4; 4-(3-Oxo-4-morpholinyl)aniline-d4; 4-(4-Aminophenyl)morpholin-3-one-d4
IUPAC Name	4-(4-amino-2,3,5,6-tetradeuteriophenyl)morpholin-3-one
Related CAS	438056-69-0 (unlabelled)
Canonical SMILES	C1COCC(=O)N1C2=CC=C(C=C2)N
InChI	InChI=1S/C10H12N2O2/c11-8-1-3-9(4-2-8)12-5-6-14-7-10(12)13/h1-4H,5-7,11H2/i1D,2D,3D,4D
InChI Key	MHCRLDZZHOVFEE-RHQRLBAQSA-N
Boiling Point	502.3±45.0 °C at 760 mmHg
Purity	95% by HPLC; 98% atom D
Density	1.3±0.1 g/cm3
Solubility	Soluble in Chloroform, Methanol
Appearance	Off-white Solid
Storage	Store at 2-8°C

4-(4-Aminophenyl)-3-morpholinone-[d4], a deuterated morpholinone analogue, plays a pivotal role in research and development within the bioscience industry. Here are the key applications:

Metabolic Flux Analysis: Delving into metabolic intricacies, 4-(4-Aminophenyl)-3-morpholinone-[d4] serves as a stable isotope-labeled compound, tracing metabolic pathways with precision. By integrating this deuterated analogue, researchers can meticulously monitor metabolite distribution and turnover, unraveling the complexities of metabolic networks and gaining insights into cellular metabolism.

Pharmacokinetics: A cornerstone of pharmacokinetic studies, this deuterated compound facilitates the analysis of drug absorption, distribution, metabolism, and excretion (ADME). With its stability and distinctive mass, it acts as an optimal internal standard in mass spectrometry assays, ensuring precise measurement and interpretation of drug behavior within the body, advancing drug research and development.

Biochemical Research: In the realm of biochemical investigations, 4-(4-Aminophenyl)-3-morpholinone-[d4] plays a crucial role in studying enzyme kinetics and inhibitor effects. Providing a labeled substrate, researchers can meticulously track enzymatic reactions and identify potential modulators, vital for drug discovery and elucidating enzyme mechanisms, driving advancements in therapeutic interventions.