Name: 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione-[d4]
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-006568

Molecular Formula: C8H6D4O4

Molecular Weight: 174.19

Chemical Structure

Description	6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione-d4 is a labelled analogue of 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione (D471415), which is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism). 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione-d4 is also an intermediate in synthesizing 2-(Hydroxymethyl)butanoic-d5 Acid (H946457), which is used as a substrate to study the activity of 2-methyl-3hydroxybutyryl-CoA dehydrogenase deficiency in patients and carriers.
Synonyms	cyclic Isopropylidene 1,1-cyclopropanedicarboxylate-D4; 1,1-Cyclopropanedicarboxylic Acid Cyclic Isopropylidene Ester-d4; 1,1-Cyclopropanedicarboxylic Acid Cyclic 1-Methylethylidene Ester-d4; 2,2-Propanediol Cyclic 1,1-Cyclopropanedicarboxylate-d4; 6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione-d4
IUPAC Name	6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione-1,1,2,2-d4
Related CAS	5617-70-9 (unlabelled)
Purity	>98%
Solubility	Soluble in Acetone, Alcohols, Dichloromethane
Appearance	Beige Solid
Storage	Store at -20°C