Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-006568 |
Molecular Formula: C8H6D4O4 |
Molecular Weight: 174.19 |
Chemical Structure |
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Description | 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione-d4 is a labelled analogue of 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione (D471415), which is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism). 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione-d4 is also an intermediate in synthesizing 2-(Hydroxymethyl)butanoic-d5 Acid (H946457), which is used as a substrate to study the activity of 2-methyl-3hydroxybutyryl-CoA dehydrogenase deficiency in patients and carriers. |
Synonyms | cyclic Isopropylidene 1,1-cyclopropanedicarboxylate-D4; 1,1-Cyclopropanedicarboxylic Acid Cyclic Isopropylidene Ester-d4; 1,1-Cyclopropanedicarboxylic Acid Cyclic 1-Methylethylidene Ester-d4; 2,2-Propanediol Cyclic 1,1-Cyclopropanedicarboxylate-d4; 6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione-d4 |
IUPAC Name | 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione-1,1,2,2-d4 |
Related CAS | 5617-70-9 (unlabelled) |
Purity | >98% |
Solubility | Soluble in Acetone, Alcohols, Dichloromethane |
Appearance | Beige Solid |
Storage | Store at -20°C |
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