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Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

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Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

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Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

A-887826-[d8]

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General Information
Catalog: BLP-003172
CAS: 1794753-88-0
Molecular Formula: C26H21D8ClN4O3
Molecular Weight: 489.04

Chemical Structure

Description	The labelled analogue of A 887826. A 887826 is a potent voltage-dependent NaV1.8 channel blocker (IC50 = 11 nM in recombinant human NaV1.8 channels). A 887826 is effective on reducing tactile allodynia in neuropathic rat models.
Synonyms	5-(4-Butoxy-3-chlorophenyl)-N-[[2-(4-morpholinyl-d8)-3-pyridinyl]methyl]-3-pyridinecarboxamide; A 887826-d8
IUPAC Name	5-(4-butoxy-3-chlorophenyl)-N-[[2-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)pyridin-3-yl]methyl]pyridine-3-carboxamide
Related CAS	1266212-81-0 (unlabelled)
Canonical SMILES	CCCCOC1=C(C=C(C=C1)C2=CC(=CN=C2)C(=O)NCC3=C(N=CC=C3)N4CCOCC4)Cl
InChI	InChI=1S/C26H29ClN4O3/c1-2-3-11-34-24-7-6-19(15-23(24)27)21-14-22(17-28-16-21)26(32)30-18-20-5-4-8-29-25(20)31-9-12-33-13-10-31/h4-8,14-17H,2-3,9-13,18H2,1H3,(H,30,32)/i9D2,10D2,12D2,13D2
InChI Key	JPJGFWKHSMUKFO-YPGVYFNXSA-N