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Application Area
Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic
Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry
Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Acipimox-[d4]

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General Information
Catalog: BLP-003214
CAS: 1246816-28-3
Molecular Formula: C6H2D4N2O3
Molecular Weight: 158.15
Chemical Structure
Acipimox-[d4]
Description Labelled Acipimox. Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as standard doses of nicotinic acid. Acipimox inhibits the production of triglycerides by the liver and the secretion of VLDL cholesterol, which leads indirectly to a modest reduction in LDL and increase in HDL cholesterol.
Synonyms 5-Methyl-2-pyrazinecarboxylic Acid 4-Oxide-d4; 5-Methylpyrazinecarboxylic Acid 4-Oxide-d4; K 9321-d4; Olbemox-d4; Olbetam-d4
IUPAC Name 3-deuterio-4-oxido-5-(trideuteriomethyl)pyrazin-4-ium-2-carboxylic acid
Related CAS 51037-30-0 (unlabelled)
Canonical SMILES CC1=CN=C(C=[N+]1[O-])C(=O)O
InChI InChI=1S/C6H6N2O3/c1-4-2-7-5(6(9)10)3-8(4)11/h2-3H,1H3,(H,9,10)/i1D3,3D
InChI Key DJQOOSBJCLSSEY-VYMTUXDUSA-N
Melting Point >170°C (dec.)
Solubility Soluble in Methanol (Slightly), Water (Slightly)
Appearance Off-white to Light Beige Solid
Storage -20°C
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