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Alpelisib-[d9]

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General Information
Catalog: BLP-013438
Molecular Formula: C19H13D9F3N5O2S
Molecular Weight: 450.47

Chemical Structure

Description	Alpelisib-[d9] is the labelled analogue of Alpelisib. Alpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. Alpelisib specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents.
Synonyms	Alpelisib-d9; BYL719-d9; Piqray-d9
Related CAS	1217486-61-7 (unlabelled)
Purity	>95%; 98% atom D