Ammonium-[d7] acetate

Ammonium-[d7] acetate is a deuterated chemical compound widely used in scientific research, particularly in analytical chemistry and molecular biology. Here are some key applications of Ammonium-[d7] acetate:

Mass Spectrometry: In mass spectrometry, Ammonium-[d7] acetate is employed as a deuterated internal standard or in buffer solutions to assist in the identification and quantification of metabolites and other small molecules. Its deuterium-labeled nature enhances the accuracy of mass spectrometric analysis by providing clear spectral separation from naturally occurring isotopes. This ensures precise and reliable data for complex sample analyses in metabolomics and proteomics.

NMR Spectroscopy: This compound is instrumental in nuclear magnetic resonance (NMR) spectroscopy, where it is used to reduce peak overlap by providing a deuterated solvent environment. It serves as a non-interfering reference compound in the study of deuterium exchange and dynamic processes in samples. By incorporating Ammonium-[d7] acetate, researchers can gain clearer insights into molecular structures and dynamics.

Pharmaceutical Research: In the pharmaceutical industry, Ammonium-[d7] acetate is utilized in the synthesis and analysis of labeled compounds for drug discovery and development. It aids in tracing metabolic pathways and understanding drug interactions by serving as a stable isotope tracer. This helps in optimizing drug design and ensuring the safety and efficacy of pharmaceutical compounds.

Biochemical Assays: Ammonium-[d7] acetate is used in various biochemical assays to study enzymatic reactions and metabolic fluxes. Its isotopic labeling allows for the precise tracking and quantification of biochemical changes in complex systems. Researchers leverage this information to explore the intricacies of metabolic networks and devise strategies for biotechnological applications.