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Ammonium Sulfate-[d8]

General Information
Catalog: BLP-009177
CAS: 13814-01-2
Molecular Formula: D8N2O4S
Molecular Weight: 140.19
Chemical Structure
Ammonium Sulfate-[d8]
Description Ammonium Sulfate-[d8], is the labelled analogue of Ammonium sulfate, Ammonium Sulfate is used as an acidity regulator in flours and breads.
Synonyms ammonium-d8sulphate; AMMONIUM SULFATE (D8); AMMONIUM-D8 SULFATE; (AMMONIUM SULFATE)-D8, 98+ ATOM % D
IUPAC Name tetradeuterioazanium;sulfate
Related CAS 7783-20-2 (unlabelled)
Canonical SMILES [NH4+].[NH4+].[O-]S(=O)(=O)[O-]
InChI InChI=1S/2H3N.H2O4S/c;;1-5(2,3)4/h2*1H3;(H2,1,2,3,4)/i/hD8
InChI Key BFNBIHQBYMNNAN-KTOHAENGSA-N
Melting Point >280°C (dec.) (lit.)
Purity 98% atom D

Ammonium Sulfate-[d8], a deuterated variant of ammonium sulfate, is widely employed in scientific research for various purposes. Here are major applications of Ammonium Sulfate-[d8] presented with high perplexity and burstiness:

NMR Spectroscopy: In the realm of nuclear magnetic resonance (NMR) spectroscopy, Ammonium Sulfate-[d8] serves as a critical isotopic label. The incorporation of deuterium (d8) isotopes in place of hydrogens plays a pivotal role in minimizing background noise and enhancing signal clarity during NMR experiments. This invaluable tool enables researchers to discern the intricate structures of complex molecules and delve into the interactions at the molecular level.

Protein Crystallization: Within the domain of protein research, Ammonium Sulfate-[d8] acts as a key precipitant in protein crystallization processes. By establishing a controlled environment conducive to protein crystal formation, it facilitates the growth of high-quality crystals essential for X-ray crystallography investigations. This method aids scientists in unraveling the structures of proteins and gaining profound insights into their functional mechanisms through meticulous analysis.

Biochemical Studies: Ammonium Sulfate-[d8] plays a pivotal role in biochemical assays, particularly in the realm of isotope labeling and tracer studies. Its deuterium composition enables researchers to meticulously monitor and quantify metabolic pathways and processes with exceptional precision. This capability is paramount for unraveling the complexities of biochemical networks and shedding light on the dynamic nature of metabolism within living organisms.

Pharmaceutical Research: In the sphere of drug development, Ammonium Sulfate-[d8] finds utility in the synthesis of deuterated compounds. Deuterated drugs are of great interest due to their potential for improved pharmacokinetic properties and reduced toxicity profiles. Additionally, this deuterated compound aids in tracing drug metabolism and distribution patterns during preclinical research, offering valuable insights into the behavior of pharmaceutical compounds within biological systems.

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