| Description |
Amoxicillin-[13C6] is the labelled analogue of Amoxicillin. Amoxicillin is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. It is usually the drug of choice within the class because it is better-absorbed, following oral administration, than other β-lactam antibiotics. Amoxicillin is susceptible to degradation by β-lactamase-producing bacteria, which are resistant to a narrow spectrum of β-lactam antibiotics, such as penicillin. |
| Synonyms |
[13C6]-Amoxicillin; Amoxicillin-13C6; CTK8F7754; (2S,6R)-6-((R)-2-amino-2-(4-hydroxyphenyl-1,2,3,4,5,6-13C6)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid-13C6; AMPC-13C6; Helvamox-13C6; Pasetocin-13C6; Penimox-13C6; Zamocillin-13C6 |
| IUPAC Name |
(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxy(1,2,3,4,5,6-13C6)cyclohexa-1,3,5-trien-1-yl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Related CAS |
26787-78-0 (unlabelled)
|
| Canonical SMILES |
CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)C(=O)O)C |
| InChI |
InChI=1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1/i3+1,4+1,5+1,6+1,7+1,8+1 |
| InChI Key |
LSQZJLSUYDQPKJ-FKFDIMAKSA-N |
| Melting Point |
> 170 °C (dec.) |
| Solubility |
Slightly soluble in Aqueous Acid, DMSO, Methanol (Heated); Very slightly soluble in Water |
| Appearance |
White to Off-white Solid |
| Storage |
-20 °C under inert atmosphere |
![Amoxicillin-[13C6]](/isotope.v1/images/structure-default.jpg)
