CAS 1346602-69-4 Anipamil-[d25] Hydrochloride

General Information
Catalog: BLP-003316
CAS: 1346602-69-4
Molecular Formula: C34H28D25ClN2O2
Molecular Weight: 582.40

General Information

Catalog: BLP-003316

CAS: 1346602-69-4

Molecular Formula: C34H28D25ClN2O2

Molecular Weight: 582.40

Chemical Structure

Description	A labelled long-acting analogue of Verapamil with antiarrhythmic and antihypertensive activity.
Synonyms	α-(Dodecyl-d25)-3-methoxy-α-[3-[[2-(3-methoxyphenyl)ethyl]methylamino]propyl]benzeneacetonitrile Hydrochloride
IUPAC Name	3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,14-pentacosadeuterio-2-(3-methoxyphenyl)-2-[3-[2-(3-methoxyphenyl)ethyl-methylamino]propyl]tetradecanenitrile;hydrochloride
Related CAS	83200-10-6 (free base)
Canonical SMILES	CCCCCCCCCCCCC(CCCN(C)CCC1=CC(=CC=C1)OC)(C#N)C2=CC(=CC=C2)OC.Cl
InChI	InChI=1S/C34H52N2O2.ClH/c1-5-6-7-8-9-10-11-12-13-14-23-34(29-35,31-19-16-21-33(28-31)38-4)24-17-25-36(2)26-22-30-18-15-20-32(27-30)37-3;/h15-16,18-21,27-28H,5-14,17,22-26H2,1-4H3;1H/i1D3,5D2,6D2,7D2,8D2,9D2,10D2,11D2,12D2,13D2,14D2,23D2;
InChI Key	SPIVBBPTKHDDSC-IUXSXPFZSA-N
Solubility	Soluble in Chloroform, Dichloromethane, DMSO
Storage	2-8°C

Anipamil-[d25] Hydrochloride, an isotopically labeled compound utilized primarily in scientific research, offers a myriad of applications across various disciplines. Here are key applications of Anipamil-[d25] Hydrochloride, presented with a high degree of perplexity and burstiness:

Pharmacokinetic Studies: Integral to understanding drug metabolism and distribution, Anipamil-[d25] Hydrochloride is a cornerstone of pharmacokinetic research. The deuterium labeling enables meticulous tracking of the compound within biological systems, facilitating clear differentiation from naturally occurring analogs. These detailed insights play a pivotal role in shaping dosing regimens and unraveling potential drug interactions, laying the foundation for optimized therapeutic treatments.

Calcium Channel Blocker Research: As a derivative of Anipamil, Anipamil-[d25] Hydrochloride shines in the exploration of calcium channel blockers, crucial components in the management of cardiovascular conditions. Researchers harness this labeled compound to delve into the interactions and efficacy of Anipamil analogs, aiming to reduce blood pressure and avert heart-related complications. This cutting-edge research not only sheds light on cardiovascular therapies but also propels the advancement of innovative treatment strategies.

Drug Development: Serving as a gold standard in the realm of pharmaceutical research, Anipamil-[d25] Hydrochloride plays a pivotal role in the development of novel therapeutic agents. Its precise chemical properties render it invaluable for analytical method development and validation. By juxtaposing unlabeled and labeled variants, researchers ensure the utmost accuracy and reliability in drug formulation and testing, underpinning the foundation of efficacious pharmaceutical solutions.

Isotope Dilution Analysis: In the domain of analytical chemistry, Anipamil-[d25] Hydrochloride takes center stage in isotope dilution mass spectrometry for quantifying drug concentrations and exploring metabolic pathways. The stable deuterium atoms act as discerning isotope markers, facilitating precise quantification of the compound within intricate biological matrices. This sophisticated technique is indispensable for clinical investigations and drug monitoring, offering invaluable insights into the intricate dynamics of drug interactions and metabolic pathways.