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Apixaban-[13C,d7]

General Information
Catalog: BLP-003322
Molecular Formula: C24[13C]H18D7N5O4
Molecular Weight: 467.53
Chemical Structure
Apixaban-[13C,d7]
Description Isotopic labelled form of Apixaban. Apixaban (INN, trade name Eliquis) is an anticoagulant for the prevention of venous thromboembolism and the prevention of stroke in atrial fibrillation. It is a direct factor Xa inhibitor. Apixaban has been available in Europe since May 2011. The drug was developed in a joint venture by Pfizer and Bristol-Myers Squibb.
Synonyms 1-(4-methoxyphenyl)-7-oxo-6-{4-[2-oxo(2-13C,3,4,4,5,5,6,6-D7)piperidin-1-yl]phenyl}1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine-3-carboxamide
IUPAC Name 6-[4-(2,2,3,3,4,4,5-heptadeuterio-6-oxo(6-13C)azinan-1-yl)phenyl]-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide
Related CAS 503612-47-3 (unlabelled)
Canonical SMILES COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N
InChI InChI=1S/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32)/i2D2,3D2,4D,14D2,21+1
InChI Key QNZCBYKSOIHPEH-IJPQQSHYSA-N
Purity > 98%

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