| Description |
Labelled Arachidonic acid. Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. |
| Synonyms |
(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic Acid-d11; (all-Z)-5,8,11,14-Eicosatetraenoic Acid-d11; 5,8,11,14-all-cis-Eicosatetraenoicmmunocytophyte-d11; Immunocytophyte-d11; all-cis-5,8,11,14-Eicosatetraenoic Acid-d11; cis-5,8,11,14-Eicosatetraenoic Acid-d11 |
| IUPAC Name |
(5Z,8Z,11Z,14Z)-16,16,17,17,18,18,19,19,20,20,20-undecadeuterioicosa-5,8,11,14-tetraenoic acid |
| Related CAS |
506-32-1 (unlabelled)
|
| Canonical SMILES |
CCCCCC=CCC=CCC=CCC=CCCCC(=O)O |
| InChI |
InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-/i1D3,2D2,3D2,4D2,5D2 |
| InChI Key |
YZXBAPSDXZZRGB-MBZQHBQHSA-N |
| Boiling Point |
407.5±0.0 °C at 760 mmHg |
| Purity |
98% by CP; 98% atom D |
| Density |
0.9±0.1 g/cm3 |
| Appearance |
Ethanol |
| Shelf Life |
3 months |
| Storage |
Store at -20°C |
![Arachidonic Acid-[d11]](/isotope.v1/images/structure-default.jpg)
