Arbidol-[d6] Hydrochloride - Isotope / BOC Sciences

General Information
Catalog: BLP-003337
Molecular Formula: C22H20D6BrClN2O3S
Molecular Weight: 519.91

General Information

Catalog: BLP-003337

Molecular Formula: C22H20D6BrClN2O3S

Molecular Weight: 519.91

Chemical Structure

Description	Arbidol-[d6] Hydrochloride is a labelled compound of Arbidol HCl. Arbidol HCl is an antiviral treatment for influenza infection.
Synonyms	6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester Hydrochloride-d6; Arbidol Hydrochloride-d6; ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indole-3-carboxylate hydrochloride hydrate
Related CAS	131707-23-8 (unlabelled)
Canonical SMILES	CCOC(=O)C1=C(N(C2=CC(=C(C(=C21)CN(C)C)O)Br)C)CSC3=CC=CC=C3.Cl
InChI	InChI=1S/C22H25BrN2O3S.ClH/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3;/h6-11,26H,5,12-13H2,1-4H3;1H
InChI Key	OMZHXQXQJGCSKN-UHFFFAOYSA-N
Melting Point	>149°C (dec.)
Purity	>98%
Appearance	Off-white to Pale Beige Solid
Storage	Hygroscopic, Refrigerator, under inert atmosphere

Arbidol-[d6] Hydrochloride, a stable isotope-labeled antiviral compound utilized in scientific research, holds significant applications in various fields. Here are the key applications of Arbidol-[d6] Hydrochloride:

Pharmacokinetics and Metabolism Studies: Arbidol-[d6] Hydrochloride plays a pivotal role in pharmacokinetic investigations, facilitating the monitoring of drug absorption, distribution, metabolism, and excretion. By employing this labeled compound, researchers can accurately quantify drug levels in biological samples using mass spectrometry. This detailed information is indispensable for comprehending the drug's behavior in the body and optimizing dosage regimens.

Antiviral Mechanism Research: Scientists leverage Arbidol-[d6] Hydrochloride to delve into the intricate mechanisms of antiviral action. Incorporating this labeled compound in cellular assays enables researchers to explore its interactions with viral proteins and evaluate its effectiveness in suppressing viral replication. This insightful research sheds light on the molecular pathways targeted by the drug, potentially influencing the development of cutting-edge antiviral treatments.

Drug-Drug Interaction Studies: Within the realm of pharmacology, Arbidol-[d6] Hydrochloride serves a crucial role in assessing potential interactions between different medications. Monitoring the presence and concentration of this labeled drug alongside other substances allows researchers to detect any modifications in pharmacokinetic profiles. These comprehensive studies are essential for guaranteeing the safety and efficacy of co-administered drugs, ensuring optimal patient outcomes.

Stability and Bioavailability Analysis: Researchers harness the power of Arbidol-[d6] Hydrochloride to evaluate the stability and bioavailability of antiviral formulations. By comparing the labeled and unlabeled versions of the drug, scientists can discern degradation rates and differences in bioavailability across various formulations. This robust data is vital for the development of robust and highly effective pharmaceutical products, paving the way for enhanced patient treatment options.