| Description |
Aripiprazole-[d8] is the labelled analogue of Aripiprazole. Aripiprazole, a dihydroquinolinone derivative, is an antagonist of Dopamine-2 receptor and a partial agonist of 5-HT1A receptor. It could be used as an atypical antipsychotic agent. |
| Synonyms |
Aripiprazole D8; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydro-2(1H)-quinolinone; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydrocarbostyril; Abilify-d8; Abilitat-d8; Aripiprazole-d8; OPC 14597-d8; 2(1H)-Quinolinone, 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl-2,2,3,3,5,5,6,6-d8]butoxy]-3,4-dihydro- |
| IUPAC Name |
7-[4-[2,2,3,3,5,5,6,6-octadeuterio-4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one |
| Related CAS |
129722-12-9 (unlabelled)
|
| Canonical SMILES |
C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl |
| InChI |
InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)/i11D2,12D2,13D2,14D2 |
| InChI Key |
CEUORZQYGODEFX-FUEQIQQISA-N |
| Melting Point |
132-137°C |
| Purity |
97%; ≥97% atom D |
| Solubility |
Soluble in Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Sonicated) |
| Appearance |
Pale Yellow Solid |
| Application |
An isotopic labelled form of aripiprazole which is an antagonist of Dopamine-2 receptor and a partial agonist of 5-HT1A receptor that could be used as an antipsychotic agent. |
| Shelf Life |
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly |
| Storage |
Store at -20°C |
![Aripiprazole-[d8]](https://resource.bocsci.com/structure/1089115-06-9.gif)
