| Description |
Azilsartan-[d5] is the labelled analogue of Azilsartan, which is an angiotensin II type 1 receptor antagonist and could be used against hypertension and inflammation. |
| Synonyms |
Azilsartan D5; 1-[[2'-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-(ethoxy-d5)-1H-benzimidazole-7-carboxylic Acid; 2-(Ethoxy-d5)-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic Acid; TAK 536-d5; Azilsartan O-Ethyl-d5 |
| IUPAC Name |
3-[[4-[2-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]-2-(1,1,2,2,2-pentadeuterioethoxy)benzimidazole-4-carboxylic acid |
| Related CAS |
147403-03-0 (unlabelled)
|
| Isomeric SMILES |
[2H]C([2H])([2H])C([2H])([2H])OC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)N5)C(=O)O |
| Canonical SMILES |
CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(=O)O |
| InChI |
InChI=1S/C25H20N4O5/c1-2-33-24-26-20-9-5-8-19(23(30)31)21(20)29(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-25(32)34-28-22/h3-13H,2,14H2,1H3,(H,30,31)(H,27,28,32)/i1D3,2D2 |
| InChI Key |
KGSXMPPBFPAXLY-ZBJDZAJPSA-N |
| Melting Point |
174-178°C |
| Purity |
≥98% by HPLC; ≥99% atom D |
| Solubility |
Soluble in DMSO (Slightly), Methanol (Slightly) |
| Appearance |
White to Off-white Solid |
| Shelf Life |
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly |
| Storage |
Store at 2-8°C |
![Azilsartan-[d5]](https://resource.bocsci.com/structure/1346599-45-8.gif)
