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Baloxavir-[d4]

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General Information
Catalog: BLP-003387
CAS: 2415027-80-2
Molecular Formula: C24H15D4F2N3O4S
Molecular Weight: 487.51

Chemical Structure

Ordering Information

Catalog Number	Size	Price	Stock	Quantity
BLP-003387	2 mg	$1099	In stock

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Description

Baloxavir-[d4] is an isotope compound of Baloxavir. Baloxavir marboxil is a first-in-class, one-dose oral medicine with a novel proposed mechanism of action that has demonstrated efficacy in a wide range of influenza viruses, including in vitro activity against oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies. Baloxavir is a polymerase acidic, cap-dependent, endonuclease inhibitor that is indicated for the treatment of acute uncomplicated influenza in patients aged 12 years and older who have been symptomatic for no more than 48 hours. It blocks viral proliferation by binding to one of two endonuclease binding sites, inhibiting the initiation of mRNA synthesis for both influenza A and influenza B strains. Baloxavir can interact with polyvalent cation-containing products, which can decrease its plasma concentration.

Related CAS

1985605-59-1 (unlabelled)