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BMS 599626-[d4]

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General Information
Catalog: BLP-003484
CAS: 1330172-72-9
Molecular Formula: C27H23D4FN8O3
Molecular Weight: 534.58

Chemical Structure

Description	A labelled analogue of BMS 599626. AC480, also known as BMS-599626, is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50 =22, 32 and 190 nM, respectively) with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.
Synonyms	N-[4-[[1-[(3-Fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamic Acid (3S)-3-Morpholinylmethyl-d4 Ester; AC 480-d4
Related CAS	714971-09-2 (unlabelled)