Name: Cabozantinib-[d4]
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-002126

Molecular Formula: C28H20D4FN3O5

Molecular Weight: 505.54

Chemical Structure

Description	Cabozantinib-[d4], is the labelled analogue of Cabozantinib. Cabozantinib is a medication used to treat medullary thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma. It is a small molecule inhibitor of the tyrosine kinases c-Met and VEGFR2, and also inhibits AXL and RET.
Synonyms	N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl-2,3,5,6-d4)cyclopropane-1,1-dicarboxamide; Cabozantinib D4; N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl-2,3,5,6-d4)-1,1-cyclopropanedicarboxamide; Cabozantinib-d4; Cabozantinib D4 (Cyclopropane-ring-D4)
IUPAC Name	N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-d4-1,1-dicarboxamide
Related CAS	849217-68-1 (unlabelled)
Canonical SMILES	O=C(C1(C(N)=O)C([2H])([2H])C1([2H])[2H])N(C2=CC=C(OC3=CC=NC4=CC(OC)=C(OC)C=C34)C=C2)C5=CC=C(F)C=C5
InChI	InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)31-14-11-23(21)37-20-9-7-19(8-10-20)32(18-5-3-17(29)4-6-18)27(34)28(12-13-28)26(30)33/h3-11,14-16H,12-13H2,1-2H3,(H2,30,33)/i12D2,13D2
InChI Key	UXJDYCVBZLEFIC-IDPVZSQYSA-N
Purity	>95%
Storage	Store at 2-8 °C