| Description |
Candesartan Cilexetil-[d11], is the labelled analogue of Candesartan Cilexetil, which is a prodrug that is activated to candesartan by ester hydrolysis during gastrointestinal absorption. Candesartan is an angiotensin receptor blocker used mainly for the treatment of high blood pressure and congestive heart failure. |
| Synonyms |
2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid 1-[[(Cyclohexyl-d11-oxy)carbonyl]oxy]ethyl Ester; Atacand-d11; Blopress-d11; TCV 116-d11; Candesartan Cilexetil D11 |
| IUPAC Name |
1-(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)oxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate |
| Related CAS |
145040-37-5 (unlabelled)
|
| Canonical SMILES |
CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC(C)OC(=O)OC6CCCCC6 |
| InChI |
InChI=1S/C33H34N6O6/c1-3-42-32-34-28-15-9-14-27(31(40)43-21(2)44-33(41)45-24-10-5-4-6-11-24)29(28)39(32)20-22-16-18-23(19-17-22)25-12-7-8-13-26(25)30-35-37-38-36-30/h7-9,12-19,21,24H,3-6,10-11,20H2,1-2H3,(H,35,36,37,38)/i4D2,5D2,6D2,10D2,11D2,24D |
| InChI Key |
GHOSNRCGJFBJIB-XLHVCENVSA-N |
| Boiling Point |
843.3±75.0 °C at 760 mmHg |
| Melting Point |
>96°C (dec.) |
| Purity |
95% (CP); 98% atom D |
| Density |
1.4±0.1 g/cm3 |
| Solubility |
Soluble in DMSO, Methanol |
| Appearance |
White to Off-white Solid |
| Storage |
Store at -20°C |
![Candesartan Cilexetil-[d11]](/isotope.v1/images/structure-default.jpg)
