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Capmatinib-[13C,d3]

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Capmatinib-[13C,d3]

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General Information
Catalog: BLP-014042
Molecular Formula: C22[13C]H14D3FN6O
Molecular Weight: 416.4

Chemical Structure

Description	Capmatinib-[13C,d3] is a labelled capmatinib. Capmatinib is an orally bioavailable inhibitor of the proto-oncogene c-Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. It selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways.
Synonyms	[13C,d3]-INCB28060; [13C,d3]-UNII-TY34L4F9OZ; 2-fluoro-N-(methyl-13C-d3)-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide; 2-fluoro-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]-N-(trideuterio(113C)methyl)benzamide
Related CAS	1029712-80-8 (unlabelled)
Purity	≥99% atom 13C; ≥98% atom D