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Chlorotrianisene-[trimethoxy-d9]

General Information
Catalog: BLP-011838
CAS: 1276197-26-2
Molecular Formula: C23H12D9ClO3
Molecular Weight: 389.93
Chemical Structure
Chlorotrianisene-[trimethoxy-d9]
Description Chlorotrianisene-[trimethoxy-d9] is the labelled analogue of Chlorotrianisene, which is a non-steroidal estrogen and could be used in the treatment of menopause as well as prostate cancer.
Synonyms Chlorotrianisene-d9 (trimethoxy-d9); Chlortrianizen-d9; Chlortrianisestrol-d9; TACE-d9; Chlorestrolo-d9; 1-[1-chloro-2,2-bis(4-methoxyphenyl)ethenyl]-4-methoxybenzene-d9
IUPAC Name 4,4',4''-(2-chloroethene-1,1,2-triyl)tris((methoxy-d3)benzene)
Related CAS 569-57-3 (unlabelled)
Purity 95% by HPLC; 98% atom D
Storage Store at -20°C

Chlorotrianisene-[trimethoxy-d9], a synthetic estrogen with specialized labeling, finds applications in diverse research and preclinical settings. Here are the key applications of Chlorotrianisene-[trimethoxy-d9]:

Hormone Replacement Therapy Research: Delving into hormone replacement therapies, Chlorotrianisene-[trimethoxy-d9] serves as a valuable tool, particularly in investigations involving postmenopausal women. By scrutinizing its effects, researchers gather crucial data on efficacy and safety parameters, which in turn contribute to the enhancement of therapeutic approaches. This aids in refining treatment protocols and elevating the quality of life for individuals undergoing such therapies.

Receptor Binding Studies: Within the realm of receptor binding assays, this labeled synthetic compound assumes importance in unraveling the intricate interactions between estrogens and their receptors. Through the utilization of Chlorotrianisene-[trimethoxy-d9], researchers quantify the binding affinities and dynamics of these interactions, providing pivotal insights for the development of selective estrogen receptor modulators (SERMs) and elucidating receptor mechanisms with nuanced precision.

Metabolic Pathway Tracing: Chlorotrianisene-[trimethoxy-d9] emerges as a versatile tool for tracing estrogen metabolism across diverse biological systems. Its application facilitates real-time monitoring of distribution and biotransformation pathways, offering invaluable data crucial for comprehending estrogenic activities and advancing the development of pharmaceutical agents targeting metabolic pathways with sophisticated precision.

Environmental Estrogen Studies: Playing a pivotal role in evaluating the environmental impact of estrogenic compounds, this labeled estrogen compound aids researchers in assessing the presence and dynamics of estrogen-like substances in water and soil samples. By utilizing Chlorotrianisene-[trimethoxy-d9], scientists can effectively track and analyze the behavior of such compounds, thereby facilitating pollution monitoring initiatives and the formulation of strategies aimed at mitigating the ecological repercussions of estrogenic contaminants.

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