CAS 203645-64-1 Choline bromide-[d13] - Isotope / BOC Sciences

General Information
Catalog: BLP-011079
CAS: 203645-64-1
Molecular Formula: C5HD13BrNO
Molecular Weight: 197.15

General Information

Catalog: BLP-011079

CAS: 203645-64-1

Molecular Formula: C5HD13BrNO

Molecular Weight: 197.15

Chemical Structure

Synonyms	Choline-d13 bromide-(N,N,N-trimethyl-d9,1,1,2,2-d4); Ethan-1,1,2,2-d4-aminium,2-hydroxy-N,N,N-tri(methyl-d3)-, bromide (9CI); 2-Hydroxy-N,N,N-tris[(2H3)methyl](2H4)ethan-1-aminium bromide
IUPAC Name	(1,1,2,2-tetradeuterio-2-hydroxyethyl)-tris(trideuteriomethyl)azanium;bromide
Related CAS	1927-06-6 (unlabelled)
Isomeric SMILES	[2H]C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])O.[Br-]
Canonical SMILES	C[N+](C)(C)CCO.[Br-]
InChI	InChI=1S/C5H14NO.BrH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1/i1D3,2D3,3D3,4D2,5D2;
InChI Key	JJCWKVUUIFLXNZ-TYBPHYHNSA-M
Purity	98% atom D
Storage	Store at -20°C

Choline bromide-[d13], a versatile labeled compound, is a cornerstone in research and development, especially in fields requiring isotopic labeling for analytical purposes. Here are key applications of choline bromide-[d13] presented with a high degree of perplexity and burstiness:

Stable Isotope Tracing: Serving as a fundamental tool in metabolic studies, choline bromide-[d13] emerges as an essential element for tracing the intricate pathways and transformations of choline within biological systems. Through its stable isotopic label, researchers meticulously track the flux and dispersion of choline across a myriad of metabolic processes. This nuanced data is crucial for unraveling the mysterious intricacies of choline metabolism and its intricate dance within the realms of both health and disease.

NMR Spectroscopy: Rising to prominence as the gold standard in nuclear magnetic resonance (NMR) spectroscopy, choline bromide-[d13] stands as a steadfast cornerstone for chemical shift analysis. Its deuterium-laden hydrogen atoms provide unparalleled spectral resolution, enabling the clear delineation of choline and its diverse derivatives amid complex mixtures. This application reigns supreme for structural elucidation and rigorous quality control within the domains of chemical and pharmaceutical research, setting the stage for groundbreaking discoveries.

Pharmacokinetics and Bioavailability Studies: Taking a central role in drug development, choline bromide-[d13] occupies a pivotal position in dissecting the pharmacokinetic profiles and bioavailability of choline-based compounds. Through meticulous observation of the isotopic label, scientists unveil the nuances of absorption, distribution, metabolism, and excretion within living organisms. This invaluable data streamlines the optimization of dosage regimens and fortifies the therapeutic efficacy of choline-centric pharmaceuticals, ushering in a new era of precision medicine.

Mass Spectrometry: Assuming a crucial role in mass spectrometry, the labeled compound emerges as a guiding light in the quantitative analysis of choline and its metabolites. Its distinctive isotopic pattern serves as a beacon, differentiating between endogenous choline and external sources with pinpoint accuracy. This application holds critical significance in diverse domains, including clinical diagnostics, nutrition studies, and cutting-edge metabolomics research, reshaping the landscape of modern analytical methodologies and catalyzing scientific advancements.