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(R)-Cinacalcet-[d3] Hydrochloride

General Information
Catalog: BLP-002257
Molecular Formula: C22H20D3ClF3N
Molecular Weight: 396.89
Chemical Structure
(R)-Cinacalcet-[d3] Hydrochloride
Description (R)-Cinacalcet-[d3] Hydrochloride is the labelled salt of (R)-Cinacalcet. Cinacalcet is the first calcimimetic drug approved by the United States Food and Drug Administration for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease.
Synonyms (R)-Cinacalcet-D3 Hydrochloride; (R)-α-(Methyl-d3)-N-[3-[3-(trifluoromethyl)phenyl)propyl]-1-napthalenemethanamine Hydrochloride; (R)-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-(1-napthyl)ethylamine-d3 Hydrochloride; Mimpara-d3; Sensipar-d3; Cinacalcet-d3 Hydrochloride
IUPAC Name N-[(1R)-2,2,2-trideuterio-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;hydrochloride
Related CAS 364782-34-3 (unlabelled) 1228567-12-1 (free base) 226256-56-0 (unlabelled free base)
Canonical SMILES CC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
InChI InChI=1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m1./s1/i1D3;
InChI Key QANQWUQOEJZMLL-GFGUQVGFSA-N
Purity ≥98% by HPLC; 99% atom D
Solubility Soluble in Acetonitrile (Slightly), Methanol (Slightly)
Appearance White Solid
Storage Store at -20°C

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