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Application Area
Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic
Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry
Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

(R)-Cinacalcet-[d3] Hydrochloride

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General Information
Catalog: BLP-002257
Molecular Formula: C22H20D3ClF3N
Molecular Weight: 396.89
Chemical Structure
(R)-Cinacalcet-[d3] Hydrochloride
Description (R)-Cinacalcet-[d3] Hydrochloride is the labelled salt of (R)-Cinacalcet. Cinacalcet is the first calcimimetic drug approved by the United States Food and Drug Administration for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease.
Synonyms (R)-Cinacalcet-D3 Hydrochloride; (R)-α-(Methyl-d3)-N-[3-[3-(trifluoromethyl)phenyl)propyl]-1-napthalenemethanamine Hydrochloride; (R)-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-(1-napthyl)ethylamine-d3 Hydrochloride; Mimpara-d3; Sensipar-d3; Cinacalcet-d3 Hydrochloride
IUPAC Name N-[(1R)-2,2,2-trideuterio-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;hydrochloride
Related CAS 364782-34-3 (unlabelled) 1228567-12-1 (free base) 226256-56-0 (unlabelled free base)
Canonical SMILES CC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
InChI InChI=1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m1./s1/i1D3;
InChI Key QANQWUQOEJZMLL-GFGUQVGFSA-N
Purity ≥98% by HPLC; 99% atom D
Solubility Soluble in Acetonitrile (Slightly), Methanol (Slightly)
Appearance White Solid
Storage Store at -20°C
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