Inquiry List

* Name:
* Phone:
* Service & Products of Interested: [Labelled APIs] Crizotinib-[d5] (1395950-48-7)
Project Description:
* Quantity
* Email:
* Organization We recommend you to leave us your work email address so that we can serve you better. Please leave your organization information here if you don't have a work email address.
* Verification Code:

Our Highlights

Optimal Prices
Buying products on this site guarantees the best price
Flexible Batches
Flexible batch size to meet different needs of global customers
Prompt Delivery
Warehouses in multiple cities to ensure timely delivery
Quality Assurance
Strict process parameter control to ensure product quality
One-to-one Customization
One-to-one custom synthesis for special structural needs

Application Area

Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Crizotinib-[d5]

Inquiry

General Information
Catalog: BLP-012277
CAS: 1395950-48-7
Molecular Formula: C21H17D5Cl2FN5O
Molecular Weight: 455.37

Chemical Structure

Description	Crizotinib-d5 is a labelled Crizotinib, a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.
Synonyms	Crizotinib D5; 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl-d4)-1H-pyrazol-4-yl]-2-pyridinamine-d5; (R)-3-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl-d4)-1H-pyrazol-4-yl]pyridin-2-ylamine-d5; PF 02341066-d5; PF 2341066-d5
IUPAC Name	3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-6-{1-[(2,2,4,6,6-2H5)-4-piperidinyl]-1H-pyrazol-4-yl}-2-pyridinamine
Related CAS	877399-52-5 (unlabelled)
Canonical SMILES	CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
InChI	InChI=1S/C21H22Cl2FN5O/c1-12(19-15(22)2-3-16(24)20(19)23)30-18-5-4-17(28-21(18)25)13-10-27-29(11-13)14-6-8-26-9-7-14/h2-5,10-12,14,26H,6-9H2,1H3,(H2,25,28)/t12-/m1/s1/i8D2,9D2,14D
InChI Key	ZSDTZQWYOPVQMX-XDVIJSJVSA-N
Boiling Point	619.7±55.0 °C at 760 mmHg
Melting Point	200-202°C (dec.)
Purity	95% by HPLC; 95% atom D
Density	1.5±0.1 g/cm3
Appearance	Light Tan Solid