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Cycloguanil-[d6] Hydrochloride

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General Information
Catalog: BLP-002367
Molecular Formula: C11H9D6Cl2N5
Molecular Weight: 294.21

Chemical Structure

Description	Cycloguanil-[d6] Hydrochloride, is the labelled analogue of Cycloguanil Hydrochloride. Cycloguanil is an active metabolite of proguanil, produced by the cytochrome P450 2C19 isoform. It is also an inhibitor of dihydrofolate reductase (DHFR) (Kis = 0.3 and 1.5 nM for Plasmodium and human forms, respectively).
Synonyms	Cycloguanil D6 Hydrochloride
IUPAC Name	1-(4-chlorophenyl)-6,6-bis(trideuteriomethyl)-1,3,5-triazine-2,4-diamine;hydrochloride
Related CAS	152-53-4 (unlabelled)
Canonical SMILES	CC1(N=C(N=C(N1C2=CC=C(C=C2)Cl)N)N)C.Cl
InChI	InChI=1S/C11H14ClN5.ClH/c1-11(2)16-9(13)15-10(14)17(11)8-5-3-7(12)4-6-8;/h3-6H,1-2H3,(H4,13,14,15,16);1H/i1D3,2D3;
InChI Key	MOUAPRKJJUXEIE-TXHXQZCNSA-N
Solubility	Soluble in DMSO, Methanol
Appearance	White to Off-white Solid
Storage	Store at -20°C