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D-Galactitol-[1-13C]

General Information
Catalog: BLP-008118
Molecular Formula: C5[13C]H14O6
Molecular Weight: 183.17
Chemical Structure
D-Galactitol-[1-13C]
Synonyms D-Galactitol 1-13C
IUPAC Name (2S,3R,4S,5R)-hexane-1,2,3,4,5,6-hexaol-1-13C
Related CAS 608-66-2 (unlabelled)
Purity 98% by CP; 99% atom 13C
Solubility Soluble in Methanol, Water
Appearance White to Pale Yellow Solid
Storage Store at -20°C

D-Galactitol-[1-13C], a specially labeled sugar alcohol, is a key component in research pertaining to metabolic pathways. Here are the key applications of D-Galactitol-[1-13C]:

Metabolic Tracing: Employing D-Galactitol-[1-13C] in metabolic flux analysis allows researchers to trace the intricate journey of carbon atoms through diverse metabolic pathways. By monitoring the incorporation of the 13C label, insights into carbohydrate metabolism are unveiled, shedding light on crucial intermediates in the metabolic process. This knowledge is paramount for unraveling the complexities of metabolic diseases and formulating precise therapeutic interventions.

Magnetic Resonance Imaging Studies: Within the realm of MRI, D-Galactitol-[1-13C] assumes the role of a contrast agent, facilitating real-time visualization of metabolic processes. The 13C label intensifies the contrast, enabling enhanced visualization of glycolytic and other metabolic activities within tissues. This application proves invaluable for non-invasively studying metabolic functions and diagnosing specific pathologies with unparalleled precision.

Stable Isotope Experiments: In the domain of stable isotope research, D-Galactitol-[1-13C] is a vital tool for studying isotopic labeling in biomolecules across cell cultures and organisms. By unraveling the mechanisms of isotope fractionation and dissecting the metabolic network, researchers gain profound insights essential for metabolic engineering and delving into intricate biosynthetic pathways.

Enzyme Kinetics: Researchers harness the power of D-Galactitol-[1-13C] to explore the nuances of enzyme kinetics and substrate specificity. By integrating this compound into enzyme assays, the conversion rates can be meticulously monitored, unveiling the catalytic efficiencies of diverse enzymes. This aids in the characterization of enzymes crucial to carbohydrate metabolism and in the design of potent enzyme inhibitors or activators, paving the way for groundbreaking advancements in enzymology.

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