D-Mannose-[1,2-13C2]

D-Mannose-[1,2-13C2] is an isotopically labeled form of D-Mannose used in various research and diagnostic applications. Here are some key applications of D-Mannose-[1,2-13C2]:

Metabolic Tracing: Delving into carbohydrate metabolism, D-Mannose-[1,2-13C2] is a key player in metabolic tracing endeavors. By meticulously tracking the labeled carbon atoms, researchers embark on a journey through the intricate pathways and fluxes of mannose metabolism in diverse cellular and tissue landscapes. This knowledge is paramount for unraveling the mysteries of disorders like congenital disorders of glycosylation, shedding light on the complex interplay within metabolic processes.

Glycan Analysis: Within the realm of glycomics, D-Mannose-[1,2-13C2] emerges as a vital tool for studying glycan dynamics in biological systems. Harnessing the power of labeled mannose in glycoprotein studies, scientists embark on a quest to decipher the intricate world of glycosylation patterns. This cutting-edge technique offers a glimpse into the multifaceted roles of glycans in the realms of health and disease, propelling the development of glycan-centric biomarkers and therapeutic interventions to new heights.

Cell Culture Studies: In the realm of cell biology, D-Mannose-[1,2-13C2] takes center stage in cell culture investigations aimed at unraveling the mysteries of mannose uptake and utilization. By meticulously analyzing the integration of labeled mannose into cellular components, researchers unlock insights into the nuanced mechanisms dictating mannose transport and metabolism within cells. This application serves as a cornerstone for understanding cellular responses to metabolic shifts and optimizing culture conditions in the realm of biotechnological innovations.

Magnetic Resonance Imaging (MRI): Venturing into the realm of medical imaging, the labeled D-Mannose-[1,2-13C2] emerges as a potent ally in the world of magnetic resonance imaging (MRI). Acting as a contrast agent, it elevates the visualization of cellular and tissue metabolic landscapes by emitting a distinct isotopic signal. This cutting-edge application holds great promise in real-time visualization of metabolic dynamics and plays a pivotal role in diagnosing a spectrum of metabolic disorders, offering a glimpse into the intricate dance of cellular metabolism.