Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013263 |
Molecular Formula: C3[13C]3H12O6 |
Molecular Weight: 183.13 |
Chemical Structure |
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Description | D-talose-[1,2,3-13C3] is a labelled analogue of D-talose which is a C-2 epimer of galactose. D-talose has been used as a substrate to identify, differentiate and characterize ribose-5-phosphate isomerase(s) of Clostridia. |
Synonyms | D-[1,2,3-13C3]talose; D-talose-1,2,3-13C3 |
Related CAS | 2595-98-4 (unlabelled) |
D-talose-[1,2,3-13C3], a stable isotope-labeled sugar renowned for its precision in metabolic tracing studies, finds widespread use in research settings. Here are the key applications of D-talose-[1,2,3-13C3]:
Metabolic Flux Analysis: Embracing D-talose-[1,2,3-13C3] for metabolic flux analysis, researchers embark on a journey to unravel the intricate pathways of carbohydrate metabolism within cells. By integrating this labeled sugar into cellular systems, scientists embark on a precise journey to track the meandering flow of carbon atoms through metabolic pathways, shedding light on the dynamic landscape of cellular metabolism and offering insights into metabolic disorders.
NMR Spectroscopy Studies: Within the realm of NMR spectroscopy, D-talose-[1,2,3-13C3] emerges as an invaluable ally for delving into the structural mysteries of carbohydrates and their derivatives. The 13C labeling elevates the resolution and sensitivity of NMR spectra, granting researchers an exquisite lens to dissect molecular structures with meticulous detail. This application shines brightest when unraveling the intricacies of complex carbohydrates and their intricate dance with other biomolecules.
Stable Isotope-Resolved Metabolomics: With its role in stable isotope-resolved metabolomics, D-talose-[1,2,3-13C3] spearheads investigations into the metabolic destinies of carbohydrates across diverse organisms. By shadowing the journey of labeled carbon atoms through metabolic networks, scientists navigate towards revealing metabolic bottlenecks and fluxes crucial for metabolic engineering. This knowledge forms the cornerstone for crafting strategies to optimize metabolic processes for industrial applications, ushering in a new era of metabolic innovation.
Diabetes Research: In the realm of diabetes research, D-talose-[1,2,3-13C3] assumes a pivotal role in dissecting the intricacies of glucose metabolism and insulin response. By infusing experimental models with this labeled sugar, researchers unlock the secrets of glucose processing in the presence of insulin, peering into the shadows of insulin resistance. These studies serve as beacons of understanding in the realm of diabetes pathophysiology, illuminating new avenues for therapeutic interventions and paving the way for transformative approaches to combat this chronic ailment.
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