D-mannitol-[1,6-13C2]

D-mannitol-[1,6-13C2], a labeled variant of the sugar alcohol D-mannitol, finds application in metabolic research and diverse scientific inquiries. Here are the key applications of D-mannitol-[1,6-13C2]:

Metabolic Flux Analysis: Acting as a potent tracer in metabolic flux analysis, D-mannitol-[1,6-13C2] sheds light on the intricate pathways of carbohydrate metabolism. By meticulously tracing the labeled carbon atoms through metabolic reactions, researchers unveil the dynamic flow of metabolites, delving deep into the convoluted networks of metabolism. This data is indispensable for decoding the complexities of metabolic pathways and optimizing efforts in metabolic engineering.

Magnetic Resonance Imaging (MRI): Within the realm of cutting-edge medical imaging, D-mannitol-[1,6-13C2] serves as a powerful enhancer of contrast in MRI scans. The labeled carbon atoms significantly amplify the visualization of metabolic processes and tissue characteristics, offering crucial insights into disease progression. This application proves invaluable in diagnosing and monitoring diseases like cancer and neurological disorders, providing vital clues for medical interventions.

Pharmaceutical Research: In the dynamic landscape of pharmaceutical research, D-mannitol-[1,6-13C2] plays a pivotal role in unraveling the intricacies of mannitol-based drug formulations. By leveraging this labeled compound, scientists meticulously track the absorption, distribution, metabolism, and excretion of mannitol in the body. This knowledge informs the development of effective drug delivery systems and contributes to establishing safety profiles for pharmaceutical interventions, driving advancements in medical research.

Biochemistry Studies: At the forefront of biochemistry, D-mannitol-[1,6-13C2] emerges as a cornerstone for probing enzyme activities and substrate interactions. By integrating the labeled mannitol into enzymatic assays, researchers gain profound insights into the catalytic mechanisms and substrate specificity of mannitol-related enzymes. This comprehensive understanding is crucial for the development of enzyme therapies and the advancement of biocatalytic processes, fostering innovation in biochemical research.