D-Mannose-[2-13C,2-18O]

D-Mannose-[2-13C,2-18O], an isotopically labeled sugar molecule, is a versatile tool in scientific research applications. Here are the key applications of D-Mannose-[2-13C,2-18O]:

Metabolic Tracing Studies: Delving into carbohydrate metabolism pathways, researchers employ D-Mannose-[2-13C,2-18O] for metabolic tracing. By scrutinizing the labeled carbon and oxygen atoms, scientists unravel the intricate journey of mannose within cells. This exploration sheds light on metabolic fluxes and potential deviations in metabolic diseases, offering a deeper understanding of cellular processes.

Glycoprotein Analysis: In the realm of glycoprotein biosynthesis, this labeled mannose plays a pivotal role. Researchers utilize it to unravel the incorporation and processing of sugars in glycoproteins, dissecting the intricate dance of glycosylation patterns and the functions of enzymes involved. This knowledge is instrumental in deciphering diseases linked to glycoprotein synthesis and advancing glycoprotein-based therapeutic strategies, adding a layer of complexity to biomedical research.

Stable Isotope Labeling in Mass Spectrometry: Widely adopted in mass spectrometry methodologies, D-Mannose-[2-13C,2-18O] allows for precise quantification and identification of mannose-containing compounds. The unique isotope labels introduce a discernible mass shift, facilitating meticulous tracking and analysis of metabolic intermediates. This application proves invaluable in unraveling metabolic regulation nuances and deciphering enzymatic activities, contributing to a deeper understanding of biochemical processes.

Nutritional and Health Research: In the realm of nutritional and health exploration, D-Mannose-[2-13C,2-18O] serves as a valuable asset. Researchers leverage this labeled sugar to explore the absorption, distribution, and utilization of mannose within the body. By monitoring its metabolic fate and evaluating physiological effects, scientists gain insights into the role of dietary mannose in health maintenance and disease prevention, adding complexity to our understanding of nutritional sciences.