D-mannose-[2-13C,2-d]

D-mannose-[2-13C,2-d], a specialized labeled sugar molecule, finds diverse uses in research and diagnostics. Explore its key applications:

Metabolic Flux Analysis: Delving into metabolic flux analysis, D-mannose-[2-13C,2-d] emerges as a pivotal tool for tracking mannose's journey through cellular and organismal metabolic pathways. By employing this labeled sugar, scientists can meticulously monitor its integration into metabolic intermediates and eventual products, shedding light on carbohydrate metabolism complexities and unveiling critical regulatory intersections.

Glycoprotein Research: Within the realm of glycoprotein investigations, the utilization of D-mannose-[2-13C,2-d] unveils the intricacies of mannose incorporation into glycan structures. By dissecting isotope-labeled glycans through mass spectrometry, researchers unravel the dynamic landscape of glycosylation, illuminating the biosynthesis and functional roles of glycoproteins in cellular mechanisms with unparalleled depth.

Cancer Metabolism Studies: In the ever-evolving field of cancer research, D-mannose-[2-13C,2-d] emerges as a valuable asset for probing the altered carbohydrate metabolism characteristic of cancer cells. By meticulously tracking labeled mannose, scientists unravel the unique sugar utilization patterns of cancer cells compared to their normal counterparts, offering crucial insights into metabolic reprogramming in cancer and paving the way for targeted therapeutic interventions.

Diagnostic Imaging: Breaking new ground in diagnostic imaging, D-mannose-[2-13C,2-d] stands out as a versatile component for techniques like magnetic resonance imaging (MRI) and positron emission tomography (PET). The isotope label facilitates non-invasive tracking of mannose uptake and distribution in tissues, enhancing diagnostic capabilities for metabolic disorders and enabling real-time monitoring of disease progression with unparalleled precision.