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D-Altrose-[2-13C]

General Information
Catalog: BLP-007073
Molecular Formula: C5[13C]H12O6
Molecular Weight: 181.15
Chemical Structure
D-Altrose-[2-13C]
Description Isotope Labelled D-Altrose is the epimer of D-glucose at C3 and have recently been discovered to possess antioxidant properties by the suppression of reactive oxygen species production in mitochondria due to competition with D-glucose at the cellular level.
Synonyms D-[2-13C]altrose; D-Altrose-2-13C
Related CAS 1990-29-0 (non-labeled)

D-Altrose-[2-13C], a sugar molecule labeled with a carbon-13 isotope at the second position, offers valuable insights for a myriad of bioscience applications. Here are the key applications of D-Altrose-[2-13C]:

Metabolic Flux Analysis: In the realm of metabolic flux analysis, D-Altrose-[2-13C] serves as a potent tool for unraveling carbon pathways within cellular systems. Scientists can meticulously track the incorporation of the carbon-13 label, delving into the intricate metabolization of D-Altrose. This aids in deciphering metabolic networks, pinpointing crucial intermediates, and identifying potential bottlenecks that govern cellular biochemistry.

NMR Spectroscopy: The intrinsic carbon-13 labeling within D-Altrose-[2-13C] renders it an invaluable asset for nuclear magnetic resonance (NMR) spectroscopy investigations. This facilitates the acquisition of detailed structural and dynamic insights into carbohydrate molecules—crucial for unraveling the nuances of carbohydrate chemistry and elucidating their interactions within biological milieus.

Isotope Dilution Analysis: Employed in isotope dilution assays, D-Altrose-[2-13C] emerges as a reliable means to accurately quantify Altrose levels within biological samples. By juxtaposing labeled and unlabeled molecules, researchers can precisely determine the concentration and turnover kinetics of D-Altrose. This methodology proves especially beneficial in nutritional research and metabolic profiling, shedding light on the dynamics of Altrose metabolism.

Pharmaceutical Research: As an indispensable asset in pharmaceutical research, D-Altrose-[2-13C] plays a pivotal role in elucidating drug metabolism and pharmacokinetics. Through the tracking of labeled carbons, researchers gain invaluable insights into the biotransformation processes of pharmaceutical compounds. This knowledge is paramount for refining drug design, optimizing therapeutic efficacy, and ensuring the safety profile of novel pharmacological agents.

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