D-Arabinitol-[2-13C]

D-Arabinitol-[2-13C], a stable isotope-labeled compound, finds diverse applications in bioscientific and medical research. Here are the key applications of D-Arabinitol-[2-13C]:

Metabolic Flux Analysis: In the realm of metabolic flux analysis, D-Arabinitol-[2-13C] emerges as a pivotal tool for tracing and quantifying cellular metabolic pathways. By integrating this labeled sugar into biological systems, researchers can meticulously monitor its conversion and distribution across various metabolic pathways. This methodology offers profound insights into cellular metabolism, paving the way for the formulation of innovative metabolic engineering strategies.

Diagnostics in Preclinical Microbiology: Within the domain of preclinical microbiology diagnostics, D-Arabinitol-[2-13C] plays a critical role in detecting fungal infections, particularly those instigated by Candida species. Infected individuals excrete D-arabinitol in their urine, a process quantifiable through the use of this labeled compound. This non-invasive diagnostic approach serves as a valuable tool in the monitoring and effective management of fungal infections.

Metabolomics Studies: Embarking on metabolomics studies, D-Arabinitol-[2-13C] assumes a crucial position as an internal standard or tracer. This compound facilitates the precise quantification and identification of metabolites in biological specimens through mass spectrometry. Such an application holds significant importance in unraveling the comprehensive metabolic landscape of organisms and pinpointing disease biomarkers fostering advancements in the field of metabolomics.

Nutritional Biochemistry: Delving into the realm of nutritional biochemistry, D-Arabinitol-[2-13C] emerges as a key player in elucidating the absorption, distribution, metabolism, and excretion (ADME) of arabinitol in nutritional research. By scrutinizing the processing of this labeled compound within the body, researchers can glean insights into carbohydrate metabolism and the impact of dietary sugars on health. Such knowledge serves as a cornerstone for crafting nutritional guidelines and devising therapeutic dietary interventions, shaping the landscape of nutritional biochemistry research.