D-Ribitol-[2-13C]

D-Ribitol-[2-13C], a carbon-labeled sugar alcohol, finds extensive applications in scientific research, especially in metabolic and biochemical studies. Here are the key applications of D-Ribitol-[2-13C]:

Metabolic Flux Analysis: By leveraging D-Ribitol-[2-13C], scientists delve into metabolic pathways, meticulously tracing the incorporation of the labeled carbon into diverse metabolites. Through a comprehensive analysis of the 13C label's distribution, researchers unlock insights into pathway dynamics and enzyme activities, shedding light on cellular metabolism intricacies and unveiling potential targets for metabolic engineering.

Structural Biology: Within the realm of structural biology, D-Ribitol-[2-13C] plays a vital role as it can be integrated into nucleotides and nucleic acids for NMR spectroscopy investigations. The carbon-13 label offers a unique signal facilitating the unraveling of molecular structures and conformations. This capability is fundamental for deciphering the structural foundations underlying DNA and RNA functionality, uncovering their complex interactions with precision and depth.

Glycosylation Studies: In the exploration of glycosylation phenomena, D-Ribitol-[2-13C] emerges as a pivotal tool acting as a precursor for diverse sugar derivatives. By meticulously tracing the labeled carbon within glycosylated molecules, researchers embark on a journey to understand the intricate processes governing the biosynthesis and modification of glycoproteins. This knowledge is paramount for unraveling the mysteries of cell signaling, protein trafficking dynamics, and disease mechanisms intertwined with glycosylation pathways.

Pharmacokinetics: Within the realm of pharmacokinetic inquiries, D-Ribitol-[2-13C] serves as a valuable resource for tracking the absorption, distribution, metabolism, and excretion of ribitol-containing drugs or supplements. The labeled carbon enables precise quantification of these processes through cutting-edge mass spectrometry or NMR techniques. Such detailed information forms the bedrock for optimizing drug formulations and unraveling the nuanced biological effects they exert, driving innovation in pharmaceutical research and development.