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D-galactitol-[2-d]

General Information
Catalog: BLP-007009
Molecular Formula: C6H13DO6
Molecular Weight: 183.18
Chemical Structure
D-galactitol-[2-d]
Synonyms D-[2-2H]galactitol; D-[2-2H]dulcitol; D-[2-2H]dulcite; D-galactitol-2-d; D-[2-D]galactitol
IUPAC Name (2S,3R,4S,5R)-hexane-2-d-1,2,3,4,5,6-hexaol
Related CAS 608-66-2 (unlabelled)
Storage Store at -20°C

D-galactitol-[2-d], a deuterated sugar alcohol, plays a pivotal role in bioscience research and industry. Here are the key applications of D-galactitol-[2-d]:

Metabolic Pathway Tracing: Widely utilized in metabolic studies, D-galactitol-[2-d] serves as a vital tool for tracing the intricate biochemical pathways of carbohydrates. By integrating this labeled compound, researchers can meticulously track the flux and transformation of sugars within cellular systems. This methodological approach aids in unraveling the complexities of metabolic disorders and optimizing pathways for biotechnological advancements.

Diagnostics: Deuterated compounds, like D-galactitol-[2-d], find utility in diagnostic imaging and mass spectrometry applications. Serving as an internal standard for quantifying metabolic intermediates and products in biological samples, this compound is indispensable for the precise and sensitive detection of biomarkers in clinical diagnostics. Its usage enhances the accuracy and reliability of diagnostic procedures.

Drug Metabolism Studies: Within the realm of pharmacokinetics, D-galactitol-[2-d] emerges as a key player in studying drug metabolism processes, particularly for drugs metabolized via galactose or related pathways. By meticulously monitoring the incorporation and turnover of deuterium-labeled sugar, researchers glean valuable insights into drug absorption, distribution, metabolism, and excretion (ADME). This approach sheds light on crucial aspects of drug efficacy and safety.

Food and Nutritional Research: In the domain of food and nutritional research, D-galactitol-[2-d] serves as a valuable asset for investigating the metabolic impacts of dietary sugars and sugar alcohols. Researchers leverage this compound to explore how various sugar forms are metabolized in the body, offering implications for dietary guidelines and insights into conditions like diabetes and obesity. This research contributes significantly to our understanding of dietary effects on metabolic health.

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