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D-xylose-[3-13C]

General Information
Catalog: BLP-008951
Molecular Formula: C4[13C]H10O5
Molecular Weight: 151.12
Chemical Structure
D-xylose-[3-13C]
Synonyms D-[3-13C]Xylose; D-xylose-3-13C
IUPAC Name (3R,4S,5R)-tetrahydro-2H-pyran-2,3,4,5-tetraol-4-13C
Related CAS 58-86-6 (unlabelled)
Purity 98% by CP; 99% atom 13C
Solubility Soluble in Methanol, Water
Appearance White to Off-white Solid
Storage Store at -20°C

D-xylose-[3-13C], an isotopically labeled sugar widely utilized in biochemical and clinical research, serves as a cornerstone in various applications:

Metabolic Tracing Studies: In the realm of metabolic tracing studies, D-xylose-[3-13C] plays a pivotal role in unraveling the intricate pathways of carbohydrate metabolism. By integrating this specialized sugar, researchers embark on a journey to trace the metabolic destiny of D-xylose, quantifying its journey through diverse metabolic pathways using cutting-edge techniques like mass spectrometry or NMR. This application not only sheds light on disorders such as diabetes and metabolic syndrome but also offers a nuanced understanding of metabolic intricacies.

Intestinal Absorption Tests: Within clinical contexts, the utilization of D-xylose-[3-13C] emerges as a key tool for evaluating intestinal absorption capacity in patients. Through the administration of this labeled sugar and subsequent measurement of its excretion in urine or breath, physicians gain valuable insights into the integrity and functionality of the small intestine. This test proves invaluable in diagnosing conditions like malabsorption syndromes and celiac disease, showcasing the versatility and diagnostic prowess of isotopically labeled sugars.

Glycosylation Pathway Research: Delving into the realms of glycosylation pathways, D-xylose-[3-13C] stands as a critical ally in exploring the intricate world of glycoprotein and glycolipid biosynthesis. Researchers harness the power of this labeled sugar to track the integration of D-xylose into glycoconjugates, unraveling the mechanisms of glycosylation with precision. This knowledge not only unveils the secrets of congenital disorders of glycosylation but also paves the way for the development of targeted therapeutic interventions, exemplifying the transformative potential of isotopic labeling techniques.

Isotopic Labeling Techniques: At the forefront of biochemical research, D-xylose-[3-13C] emerges as an indispensable asset for isotopic labeling of biomolecules, heralding a new era of precision and insight. By embedding this sugar into cellular systems, researchers unlock the ability to label specific carbon atoms within complex molecules, facilitating in-depth exploration of biosynthetic pathways and metabolic flux. This cutting-edge technique serves as a cornerstone in advancing the fields of metabolomics and synthetic biology, offering unprecedented opportunities for exploration and discovery in the realm of biochemical sciences.

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