D-mannose-[3-d]

D-mannose-[3-d] is a simple sugar with unique properties that find applications in various fields of bioscience and medicine. Here are some key applications of D-mannose-[3-d]:

Urinary Tract Infections (UTIs): D-mannose-[3-d] is used as a therapeutic supplement to prevent and treat UTIs caused by E. coli bacteria. It works by binding to the lectins on the surface of the bacteria, preventing them from adhering to the urinary tract walls. This makes it easier for the body to flush out the bacteria, reducing infection rates and symptoms.

Glycoprotein Engineering: In biotechnology, D-mannose-[3-d] is used in the synthesis and modification of glycoproteins. These glycan structures are essential for the proper folding, stability, and function of many therapeutic proteins and enzymes. Researchers employ D-mannose-[3-d] to study glycosylation patterns and to enhance the production of recombinant glycoproteins with desired properties.

Prebiotic Function: D-mannose-[3-d] serves as a prebiotic, promoting the growth of beneficial gut bacteria. By selectively fostering the proliferation of specific microbial populations, it contributes to a healthy gut microbiome. This can improve overall digestive health, enhance nutrient absorption, and support immune function.

Research Tool in Glycobiology: D-mannose-[3-d] is utilized as a research reagent in studies focused on glycobiology and carbohydrate metabolism. By incorporating D-mannose-[3-d] into experimental protocols, scientists can investigate the role of mannose-containing polysaccharides in cell signaling, adhesion, and immune responses. This knowledge is critical for understanding diseases related to glycans and for developing relevant therapeutic approaches.