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D-Galactose-[3,5-d2]

General Information
Catalog: BLP-007012
Molecular Formula: C6H10D2O6
Molecular Weight: 182.17
Chemical Structure
D-Galactose-[3,5-d2]
Description Isotope labelled D-galactose, A C-4 epimer of Glucose found in milk and sugar beets as well as in human body. Potential use in oral treatment for nephrotic syndrome in focal and segmental glomerulosclerosis.
Synonyms (+)-Galactose-3,5-d2; D-(+)-Galactose-3,5-d2; Galactose-3,5-d2; D-[3,5-2H2]galactose; D-Galactose-3,5-d2; D-[3,5-D2]galactose
IUPAC Name (3R,4S,5R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-4,6-d2-2,3,4,5-tetraol
Related CAS 59-23-4 (unlabelled)
Solubility Soluble in Methanol, Water
Appearance White to Off-white Solid
Storage Store at -20°C

D-galactose-[3,5-d2], a deuterium-labeled sugar molecule, finds extensive use in diverse research endeavors. Here are the key applications of D-galactose-[3,5-d2]:

Metabolic Tracing: Delving into metabolic intricacies, D-galactose-[3,5-d2] emerges as a pivotal tool in tracing the convoluted pathways of galactose metabolism in cells and organisms. Through innovative isotopic labeling techniques, researchers embark on a journey to monitor the intricate incorporation and conversion of galactose in diverse metabolic processes, utilizing cutting-edge mass spectrometry or NMR technologies. This meticulous approach unfurls detailed insights into the subtle nuances of metabolic flux and regulation, shedding light on the complexity of cellular activities.

Glycoprotein Biosynthesis: Embarking on the quest to unravel the mysteries of glycoprotein biosynthesis, D-galactose-[3,5-d2] assumes a crucial role in elucidating the labyrinthine pathways of glycosylation. By integrating this deuterium-labeled sugar into glycoproteins, researchers embark on an odyssey to decipher the enigmatic role of specific sugars in shaping protein folding, stability, and functionality. This profound exploration proves indispensable in unraveling the intricacies of various biological processes, offering a key to optimizing the production of therapeutic glycoproteins.

Biochemical Pathway Elucidation: Illuminating the dark alleys of biochemical pathways linked to galactose, such as the Leloir pathway and alternative galactose metabolism routes, D-galactose-[3,5-d2] emerges as a guiding light. Researchers navigate through this intricate biochemical landscape, meticulously tracking the deuterium-labeled metabolites through a series of enzymatic reactions to map and quantify pathway intermediates. This meticulous endeavor fuels a deeper comprehension of metabolic disorders and paves the way for the development of novel therapeutic interventions.

Pharmaceutical Research: Venturing into the realm of drug development, D-galactose-[3,5-d2] stands as a cornerstone in unraveling the pharmacokinetics and pharmacodynamics of galactose-containing drugs and compounds. This labeled sugar emerges as a potent tool, facilitating precise measurements of drug absorption, distribution, metabolism, and excretion. Such intricate insights play a pivotal role in fine-tuning drug formulations, enhancing therapeutic efficacy, and laying the groundwork for breakthroughs in pharmaceutical research.

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