D-Mannose-[4-13C], a carbon-labeled monosaccharide, finds utility in diverse scientific research endeavors. Explore the key applications of D-Mannose-[4-13C] below:
Metabolic Flux Analysis: Delving into metabolic flux analysis, D-Mannose-[4-13C] serves as a crucial tool for tracing carbon flux through intricate metabolic pathways. Scientists leverage this compound to investigate carbohydrate metabolism and evaluate the activity of specific cellular pathways. Through this, they gain profound insights into the metabolic landscapes of cells, uncovering potential dysfunctions lurking within.
Glycomics Studies: In the realm of glycomics research, D-Mannose-[4-13C] takes center stage in the exploration of mannose-containing glycans, integral components of glycoproteins and glycolipids. By introducing labeled mannose into cell cultures, researchers embark on a journey to decipher glycan structures and decode the intricacies of glycosylation processes. Such knowledge is pivotal for understanding diverse biological phenomena and delving into diseases intertwined with glycosylation complexities.
NMR Spectroscopy: A valuable asset in nuclear magnetic resonance (NMR) spectroscopy, D-Mannose-[4-13C] enhances the study of carbohydrate structures and dynamics. The 13C label elevates the sensitivity and resolution of NMR signals, facilitating in-depth analyses of mannose-containing molecules. This aids in unraveling the convoluted molecular structures and interactions that govern biological systems.
Pharmacokinetics: Stepping into the realm of pharmacokinetic studies, D-Mannose-[4-13C] plays a key role in investigating the absorption, distribution, metabolism, and excretion (ADME) of mannose-based therapeutics. By monitoring the labeled mannose within biological systems, researchers glean insights into the bioavailability and metabolic destiny of drugs containing mannose. This knowledge forms the bedrock for optimizing drug formulations and designing effective dosing regimens, shaping the landscape of pharmaceutical advancements.
![D-Mannose-[4-13C]](https://resource.bocsci.com/structure/d-4-13c-mannose.gif)
